Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4627
Gene Symbol: MYH9
MYH9
0.180 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 3985
Gene Symbol: LIMK2
LIMK2
0.110 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 9814
Gene Symbol: SFI1
SFI1
0.110 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 4733
Gene Symbol: DRG1
DRG1
0.100 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
0.100 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 1124
Gene Symbol: CHN2
CHN2
0.100 GeneticVariation disease GWASDB Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. 19252134 2009
Entrez Id: 9215
Gene Symbol: LARGE1
LARGE1
0.100 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 55068
Gene Symbol: ENOX1
ENOX1
0.100 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 91445
Gene Symbol: RNF185
RNF185
0.100 GeneticVariation disease GWASDB A genome-wide association study for diabetic nephropathy genes in African Americans. 21150874 2011
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
0.320 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.600 Biomarker disease RGD In conclusion, Col prevents not only inflammatory cell infiltration via inhibition of enhanced MCP-1 and ICAM-1 expression but also ECM accumulation in DN. 19369290 2009
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.600 Therapeutic disease RGD Alpha-lipoic acid upregulates antioxidant enzyme gene expression and enzymatic activity in diabetic rat kidneys through an O-GlcNAc-dependent mechanism. 23064900 2013
Entrez Id: 213
Gene Symbol: ALB
ALB
0.600 Biomarker disease RGD Diet-induced renal changes in Zucker rats are ameliorated by the superoxide dismutase mimetic TEMPOL. 19424163 2009
Entrez Id: 213
Gene Symbol: ALB
ALB
0.600 Biomarker disease RGD The amelioration of streptozotocin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription. 19397971 2009
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.600 Biomarker disease RGD Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling. 21439372 2011
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.600 Biomarker disease RGD ACE-inhibitor suppresses the apoptosis induced by endoplasmic reticulum stress in renal tubular in experimental diabetic rats. 19301230 2009
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.600 Biomarker disease RGD Renal synthesis of urokinase type-plasminogen activator, its receptor, and plasminogen activator inhibitor-1 in diabetic nephropathy in rats: modulation by angiotensin-converting-enzyme inhibitor. 15322501 2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.600 Biomarker disease RGD Collectively, these results suggest that LAB has beneficial effects on the diabetic nephropathy in OLETF rats by decreasing blood pressure, oxidative stress, and MCP-1 expression. 18031723 2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.600 Therapeutic disease RGD Antioxidant and pro-oxidant effects of oil palm (Elaeis guineensis) leaves extract in experimental diabetic nephropathy: a duration-dependent outcome. 24074026 2013
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.600 Therapeutic disease RGD Panax notoginseng saponins protect kidney from diabetes by up-regulating silent information regulator 1 and activating antioxidant proteins in rats. 26712211 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.600 Therapeutic disease RGD Cupuaçu extract reduces nitrosative stress and modulates inflammatory mediators in the kidneys of experimental diabetes. 29336891 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
0.600 Biomarker disease RGD In the present study, we investigated the effect and molecular mechanism of the PPARgamma agonist, pioglitazone, on the progression of diabetic nephropathy in type 2 diabetic rats. 18388116 2008
Entrez Id: 213
Gene Symbol: ALB
ALB
0.600 Biomarker disease RGD Renal protective effect of chronic inhibition of COX-2 with SC-58236 in streptozotocin-diabetic rats. 21441310 2011